Hydroxypropyl Methylcellulose (HPMC) is not typically used in hand sanitizers as the primary active ingredient. Hand sanitizers are generally formulated with active antimicrobial agents such as alcohol, isopropanol, or benzalkonium chloride, which are responsible for killing bacteria and viruses on the skin. HPMC, being a cellulose-based polymer, is more commonly found in other types of formulations such as pharmaceuticals, cosmetics, construction materials, and food products.
However, in some cases, HPMC or similar polymers may be included in hand sanitizer formulations for specific purposes. Here are a few potential roles for HPMC in hand sanitizers:
Thickening Agent:
HPMC can be used as a thickening agent to increase the viscosity of the hand sanitizer gel. This helps in providing a more stable and user-friendly product by preventing it from being too runny. It also contributes to the overall sensory experience during application.
Moisturizing Properties:
HPMC can contribute to the formulation’s moisturizing properties. It may help in retaining moisture on the skin, preventing excessive dryness that can be associated with frequent use of hand sanitizers containing high concentrations of alcohol.
Film-Forming Agent:
HPMC, when included in small amounts, can contribute to the formation of a thin film on the skin. This film may enhance the residual activity of the hand sanitizer, providing an extended period of protection against pathogens.
It’s important to note that the effectiveness of a hand sanitizer primarily relies on the active antimicrobial ingredients (usually alcohol or an alternative) rather than on secondary additives like HPMC. Any inclusion of HPMC or similar substances should comply with regulatory guidelines, and the overall formulation should meet the necessary efficacy and safety standards.
Hand sanitizer formulations should adhere to guidelines set by health authorities, such as the World Health Organization (WHO) or relevant regulatory bodies in different regions, to ensure they effectively reduce the microbial load on the hands and promote user safety.
